Eczema Research Today is a free monthly online journal that collates and summarizes the latest research about Eczema, including details on dermatitis, skin rashes, medication, treatment, causes, creams.

Filaggrin mutations and allergic contact sensitization.

Hanifin JM

Department of Dermatology, Oregon Health and Science University, Center for Health and Healing, Portland, Oregon 97239, USA. hanifinj@ohsu.edu

In this issue, Novak et al. (2008) provide evidence that filaggrin barrier defects might also predispose to allergic contact dermatitis by allowing greater penetration of chemical haptens. Their report provides a fresh perspective on the issues of contact allergy, nickel sensitization, and stratum corneum defects.

Published 14 May 2008 in J Invest Dermatol, 128(6): 1362-4.
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